Best Lesbian Protagonist Movies & TV Shows

Amid the stark discord of twin cities Piltover and Zaun, two sisters fight on rival sides of a war between magic technologies and clashing convictions.

Twenty years after modern civilization has been destroyed, Joel, a hardened survivor, is hired to smuggle Ellie, a 14-year-old girl, out of an oppressive quarantine zone. What starts as a small job soon becomes a brutal, heartbreaking journey, as they both must traverse the United States and depend on each other for survival.

When a deep space freighter is damaged by a solar flare its surviving crew are stranded on a beautiful and unforgiving planet. They begin to learn the true nature of this planet as they try to survive long enough to escape or be rescued.

In a mysterious primeval land populated by dinosaurs and other extinct creatures, people from throughout human history have been resurrected. When 21st century Australian paleontologist Helena Walker awakes there after tragedy, she must learn to survive and find new allies, or die again at the hands of ruthless warlords, all while trying to uncover the true nature of their strange new world.

A group of high school students navigate love and friendships in a world of drugs, sex, trauma, and social media.

The tale of four girls who transform into legendary warriors known as Mysticons. The Mysticons must use their powers to save their realm from Necrafa, an evil queen.

A teen navigates the complexities of high school, family and her sexuality while dealing with new superpowers. Based on Charles Forsman's graphic novel.

Falling in love is tricky for teens Juliette and Calliope: One's a vampire, the other's a vampire hunter — and both are ready to make their first kill.

Follow Moiraine, a member of the shadowy and influential all-female organization called the “Aes Sedai” as she embarks on a dangerous, world-spanning journey with five young men and women. Moiraine believes one of them might be the reincarnation of an incredibly powerful individual, whom prophecies say will either save humanity or destroy it.

Unpopular best friends PJ and Josie start a high school self-defense club to meet girls and lose their virginity. They soon find themselves in over their heads when the most popular students start beating each other up in the name of self-defense.

After an au pair’s tragic death, Henry Wingrave hires a young American nanny to care for his orphaned niece and nephew who reside at Bly Manor with the estate’s chef Owen, groundskeeper Jamie and housekeeper, Mrs. Grose. But all is not as it seems at the manor, and centuries of dark secrets of love and loss are waiting to be unearthed in this chilling tale.

Picking up one year after the events of the final broadcast episode of "The Good Wife", an enormous financial scam has destroyed the reputation of a young lawyer, Maia Rindell, while simultaneously wiping out her mentor and godmother Diane Lockhart's savings. Forced out of her law firm, now called "Lockhart, Deckler, Gussman, Lee, Lyman, Gilbert, Lurie, Kagan, Tannebaum & Associates", they join Lucca Quinn at one of Chicago's preeminent law firms.

The pirate adventures of Captain Flint and his men twenty years prior to Robert Louis Stevenson’s classic “Treasure Island.” Flint, the most brilliant and most feared pirate captain of his day, takes on a fast-talking young addition to his crew who goes by the name John Silver. Threatened with extinction on all sides, they fight for the survival of New Providence Island, the most notorious criminal haven of its day – a debauched paradise teeming with pirates, prostitutes, thieves and fortune seekers, a place defined by both its enlightened ideals and its stunning brutality.

During her wedding ceremony, Rachel notices Luce in the audience and feels instantly drawn to her. The two women become close friends, and when Rachel learns that Luce is a lesbian, she realizes that despite her happy marriage to Heck, she is falling for Luce. As she questions her sexual orientation, Rachel must decide between her stable relationship with Heck and her exhilarating new romance with Luce.

It's 1996 in a town called Boring, Oregon, where high school misfits in the AV and drama clubs brave the ups and downs of teenage emotions in the VHS era.

The Guardians must save Meridian from the evil sorcerer Phobos and Cedric who are searching for Phobos' sister, the long lost princess of Meridian and true heir to the throne. They later find her and the Guardians then set about saving her from Phobos. When Meridian is freed from evil and true heir takes the throne, a new mysterious sorceress named Nerissa frees Phobos' top henchmen and reforms them as the Knights of Vengeance. Once the Guardians learn more about the sorceress and her evil plan of reuniting former Guardians, they are able to defeat the Knights only to have more powerful Knights, in addition to the former Guardians attack them.

A drama centered on two women who engage in a dangerous relationship during South Africa's apartheid era.

Dark comedy about the eccentric members of the Flowers family. Maurice and Deborah are barely together but yet to divorce. They live with Maurice's batty mother and their maladjusted twin children.

An emotionally scarred highway drifter shoots a sadistic trick who rapes her, and ultimately becomes the United States' first female serial killer.

DI Cadi John and DC Owen Vaughan try to solve a case involving Mali Pryce, a young woman whose body was discovered in a stream in the woods.

Renowned musician Lydia Tár is days away from recording the symphony that will elevate her career. However, Lydia's elaborate facade begins to unravel, revealing dirty secrets and the corrosive nature of power.

The story of straight-edge literature professor Vivian who travels to Reno to get away from a relationship breakup when she falls in love with an attractive and unconventional girl named Cay.

Jefferson Pierce is a man wrestling with a secret. As the father of two daughters and principal of a charter high school that also serves as a safe haven for young people in a New Orleans neighborhood overrun by gang violence, he is a hero to his community.

A diverse group of young women navigate their lives through the male-dominated world of skateboarding in New York City. Inspired by the critically acclaimed film Skate Kitchen.

Heidi Bergman is a caseworker at Homecoming, a Geist Group facility helping soldiers transition to civilian life. Years later she has started a new life, living with her mother and working as a waitress, when a Department of Defense auditor questions why she left the Homecoming facility. Heidi quickly realizes that there's a whole other story behind the story she's been telling herself.

In a small, middle-class town in Long Island, NY, three women – and close-knit childhood friends – cope with the death of the fourth member of their group. When faced with the reality that life is short, these women pivot, and alter their current paths, by way of a series of impulsive, ill-advised and self-indulgent decisions. These pivots will strengthen their bond and prove it’s never too late to screw up your life in the pursuit of happiness.

Kate Kane, armed with a passion for social justice and a flair for speaking her mind, soars onto the streets of Gotham as Batwoman, an out lesbian and highly trained street fighter primed to snuff out the failing city's criminal resurgence. But don't call her a hero yet. In a city desperate for a savior, Kate must overcome her own demons before embracing the call to be Gotham's symbol of hope

When Hulu reboots an early 2000s family sitcom, its dysfunctional cast is forced back together and now must deal with their unresolved issues in today’s fast-changing world.

A woman's life takes an unexpected turn when she falls for her boss's wife. She must soon defend herself as she becomes entangled in a web of malice.

An investigation into a botched kidnapping uncovers long-held secrets connecting multiple characters and cultures in present day New York City.

Thirty years ago, in the sleepy community of Waterbury, a killer known as “The Executioner” murdered Sarah Bennett's parents. Now Sarah and her husband Dylan have returned to town, only to find herself the centerpiece in a series of horrifying murders centered around the seven deadly sins.

Amid the drug trade on Cape Cod, a body washes ashore and is discovered by an irreverent National Marine Fisheries Service officer, Jackie Quinones, who is determined to help solve the murder even if the state cops want her nowhere near the case.

A US soldier suffers a traumatic brain injury while fighting in Afghanistan and struggles to adjust to life back home in New Orleans. When she meets local mechanic James, the pair begin to forge an unexpected bond.

Two Mexican-American sisters from the Eastside of Los Angeles who couldn't be more different or distanced from each other are forced to return to their old neighborhood, where they are confronted by the past and surprising truth about their mother’s identity.

A series of eight monologues set in the same pub over many years of gay history in response to the 50th anniversary of the Sexual Offences Act.

A dethroned queen bee at a posh private high school strikes a secret deal with an unassuming new student to enact revenge on one another’s enemies.

A horrible creature with an insatiable appetite for human flesh feasts on a group of terrified campers.

Elliot and Beverly Mantle are twins who share everything: drugs, lovers, and an unapologetic desire to do whatever it takes — including pushing the boundaries on medical ethics — in an effort to challenge antiquated practices and bring women’s healthcare to the forefront.

When June Buckridge arrives at her London flat and announces 'They are going to murder me', her long-time lover and doll-cuddling flat mate Alice 'Childie' McNaught realizes that things are going to change. For June is referring to her character 'Sister George', a lovable nurse she portrays in a popular daytime serial. To make matters worse, the widowed executive at the BBC responsible for the decision to kill off Sister George - Mercy Croft is also a predatory lesbian who is after Childie and will stop at nothing to get what she wants.

A young woman is invited by her girlfriend, who lives in an English country mansion, to stay there with her. The estate, however, isn't quite what it seems--and neither is the friend who issued the invitation.

Three reunited sisters discover their late father planned one last scavenger hunt - an annual holiday tradition when they were young. As their sisterly bond gets rekindled, they soon learn important lessons about what they want in life and in love.

Majestic mountains, a still lake and venomous betrayals engulf a female married couple attempting to celebrate their one-year anniversary.

Lia Haddock, a journalist for American Public Radio, unravels the mystery behind the disappearance of over 300 people at a research community in Tennessee.

A lesbian bachelorette weekend goes awry when one of the brides admits she's never had an orgasm.

High School grad and all American gal, Anna, finds her purpose and herself after she hooks up with the radical feminists in The Itty Bitty Titty Committee.

When theater major Leah, brings home the special someone in her life to meet her mom, Julie, the family is met with a surprise when Pearl comes to the door. Julie tries to embrace the idea of Leah’s new love interest, but she can’t shake the feeling that something is very wrong. Julie’s suspicions lead to a startling discovery about Pearl that puts Leah in serious danger. Will Julie be able to save her daughter from an eternity of heartache before it’s too late?

Shareen and Claire, a lesbian couple living on Staten Island, find themselves ensnared in a vast conspiracy involving a ghost ship of nuclear refuse, ominous television commercials, and deadly cat food.

Reena is a young Indian American lesbian who lives and works in New York. Her sister Sarita, who is happily married, discovers that she is infertile. Reena offers to be a surrogate mother for her sister's baby, hoping to improve her relationship with their mother, who disapproves of Reena's sexual orientation. Reena has second thoughts when her girlfriend Lisa feels left out.

Ten years after ending their partnership as rock musicians, two women become re-acquainted in the course of one night.

Angie and Helen are in love. They live and work together designing women's evening wear in Vancouver. When Helen decides she wants to have a baby, the pair set out to find a suitable sperm donor.